PR240993
Description
Transparent liquid of light-yellow colour with specific odour.
Composition and pharmacological properties
An agent contains active substances: fipronil – 10%; S-methoprene – 10%. Excipients: propylene glycol.
The agent relates to combined insectoacaricidal preparations. It has an expressed action onto preimaginal and adult phase development of fleas (Ctenocephalides spp.), lice (Linognathus spp.), chewing lice (Trichodectes canis, Felicola subrostratus) and ticks (Rhipicephalus spp., Dermacentor spp., Ixodes spp.), which are parasitized on dogs and cats body.
Fipronil mode of action is in blocking of GABA-dependent receptors of parasites, disrupting transmission of nerve impulses, which result nervous breakdown in ectoparasites and lead to death. Fipronil hasn’t impact on animal central nervous system.
S-methoprene is a juvenile hormone analog, which acts as a growth regulator of insects, inhibits growth and morphologic development of insects’ on eggs stage, larva and pupa due to antagonism with ecdysone that is responsible for growth and development larva.
Oocyte action of S-methoprene is demonstrated in result of direct penetration into coat of deposited eggs.
Application | for dogs |
Volume | 3 мл |
Storage conditions | In a dry room at a temperature of 0 to 30 ° C and a relative humidity of not more than 75%. |
Expiration date | 3 years |
Indications
Prevention and treatment of dogs and cats in diseases caused by ectoparasites: fleas (Ctenocephalides spp.), lice (Linognathus spp.), chewing lice (Trichodectes canis, Felicola subrostratus) and ticks (Rhipicephalus spp., Dermacentor spp., Ixodes spp.). Prevention and treatment of cats and dogs in flea allergy dermatitis (FAD).
Dosage and Administration
The remedy is applied external, directly to the skin in areas non-available for licking (withers area and along the backbone).
The remedy is applied onto dry, intact skin. Take a single-dose pipette and holding it upright, cut off the tip. Split up animal coat in place of application and put the remedy directly onto skin between the shoulder blades at the neck base.
The remedy is used of different volume according to the minimal dose, which depends on animal's body weight.
Dosage for cats
Animal body weight, kg | Pipette volume, ml | Quantity of pipettes |
up to 4 | 0,5 | 1 |
4 to 8 | 1,0 | 1 |
over 8 | Respective combination of pipettes |
Dosage for dogs
Animal body weight, kg | Pipette volume, ml | Quantity of pipettes |
up to 4 | 0,5 | 1 |
4 to 10 | 1,0 | 1 |
10 to 20 | 2,0 | 1 |
20 to 40 | 3,0 | 1 |
over 40 | Respective combination of pipettes |
Processing of the animals is carried out during the seasonal activity of parasites in requirement, but not often than one time in 30 days.
It is required to processing periodically with respective insecticide remedies or change dog beds and carry out regular cleaning of their place of stay in purpose to prevent infestation by ectoparasites.
Contraindications
Do not administrate to sick, emaciate and weaken animals.
Do not administrate to kittens and puppies up to 8-weeks age.
Do not administrate to animals with individual hypersensitivity to remedy ingredients.
Do not use together with other insecticidal remedies.
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